Need to log in to your Nebula Genomics account but can’t figure out how? Our step-by-step guide will help you sign in to the website in three easy steps. Once you access your dashboard, you can explore the services that Nebula has to offer.
Accessing your Nebula Genomics login is simple. Follow these steps to get started:
3. Click submit, and you should be able to access the account
Don’t worry; resetting your Nebula Genomics login credentials is easy.
Click on the “Forgot Password” button.
From here, in 3 easy steps, you can reset your password and recover your Nebula Genomics account.
If you do not have an account with Nebula Genomics, you can create an account by clicking on the “Sign Up For Free” link.
Follow these steps to create a free account:
6. Nebula will send a verification email – click on the confirm button in the email.
7. Your account will be created, and you’ll be redirected to your account dashboard.
Nebula Genomics offers DNA testing services focusing on whole genome sequencing, which provides a detailed analysis of a person’s genetic makeup.
They offer reports that cover ancestry, genetic traits, and health insights.
Here’s a breakdown of their key products and services:
1. Whole-genome sequencing: Nebula Genomics focuses on sequencing 100% of your DNA, providing in-depth insights.
2. Ancestry reports: Their reports give users information about their ancestry, including regional breakdowns and potential connections to ancient populations.
3. Health insights: Nebula offers reports that assess genetic predispositions to certain conditions, physical traits, and wellness suggestions.
Nebula Genomics’ pricing model typically includes:
They occasionally offer discounts, so pricing may vary.
Nebula Genomics offers ancestry analysis through its deep genetic ancestry service, which utilizes whole genome sequencing. However, it primarily collaborates with external programs like Eurogenes and YFull for detailed ancestry insights.
The cost of Nebula Genomics’ whole genome sequencing (WGS) starts at $249 and goes up to $999. Additionally, a membership fee is required for accessing personalized reports and tools.
The company, founded by Harvard professor George Church, emphasizes privacy and data security, utilizing blockchain technology to anonymize genetic data. However, some users have reported inconsistencies in raw data analysis, so it’s advisable to approach results cautiously and verify findings through additional research.
One Reddit user writes, “Nebula has given me answers to health issues that none of my doctors have been able to figure out.”
On the other hand, several Trustpilot users have opened up about delays in receiving their orders, with one user writing, “One year later and never got my results. Nebula … have not corrected this problem.”
| Feature | Invitae | Nebula Genomics |
| Focus | Genetic testing for inherited conditions | Whole genome sequencing and health insights |
| Order process | Through a practitioner | Consumer can directly order |
| Ancestry analysis | Limited ancestry information | Collaborates with external services for ancestry |
| Pricing | $250 – $450 (insurance coverage available) | $249 – $999 |
| Data privacy | HIPPA compliance, consent, CLIA – CAP verified, de-identification of data | Blockchain and encryption, limited third party access |
Nebula Genomics is not free, but users can upload raw DNA data from other services at no cost. The primary offerings, including whole genome sequencing and access to detailed reports, require payment.
Sequencing with Nebula Genomics typically takes 4-8 weeks after sample submission. However, some users have reported longer wait times due to various factors, such as demand and processing capabilities. They usually provide regular updates on progress through their platform.
Have you ever noticed severe tooth pain and wear despite an excellent oral hygiene routine? Ten percent of adults experience bruxism, involuntary teeth grinding in their sleep. It can happen due to sleep disorders or excessive snoring. Over time, it can damage your teeth and jaws. Your genes can put you at a higher or lower risk of developing bruxism. That’s why it’s vital to understand bruxism and your possible genetic risk for it.
Bruxism can happen due to:
Some common symptoms of bruxism are:
Research has shown that teeth grinding can be genetic and run in families.
If your close relatives have bruxism, you are at risk of developing this disease.
21-50% of people with a close family member with bruxism will develop this condition.
NTRK2 and BDNF genes have a link to your risk for bruxism.
These two genes are involved in stress regulation pathways.
People with altered serotonin receptors are at an increased risk of developing bruxism.
Serotonin is a neurotransmitter that influences mood and memory.
Changes in the serotonin receptors, such as HTR2A, can decrease serotonin levels in the body.
It might result in anxiety, which is the leading cause of teeth grinding.
Common antidepressants like SSRIs can put you at risk of developing bruxism.
Stress and anxiety are the leading cause of teeth grinding.
Clenching your teeth when you are stressed or anxious is typical behavior.
It continues in your sleep as sleep bruxism.
You can also develop this condition due to genetics.
Bruxism can run in families and increase the risk of developing this condition.
Sleep disorders such as apnea can also cause teeth grinding.
Studies have shown that nearly 50% of children experience teeth grinding at night.
Teeth grinding can start as soon as teeth come in, so even toddlers and infants can suffer from bruxism.
It can occur due to:
Bruxism is both a neuromuscular and a dental disorder.
Physicians do not usually treat this disorder.
Dental surgeons and TMD specialists are better equipped to treat this condition.
Teeth grinding is often a problem in children with autism.
In addition, they often cannot communicate clearly with their caregivers.
Thus, it becomes difficult to treat them, and their oral health gets compromised.
They might also have eating and sleep disorders, aggravating the problem.
There can be several consequences if teeth grinding goes untreated:
Teeth grinding cannot be cured entirely.
Several preventive measures can relieve symptoms and decrease teeth and jaw damage.
While some people might not need help at all, here’s what you can do if your bruxism turns serious:
Chronic bruxism can compromise your oral health.
If left untreated, you might develop tooth pain and problems.
Your enamel will erode, exposing the underlying dentin.
An exposed dentin could make your teeth painfully sensitive to cold or hot foods.
Bruxism can also cause chronic jaw pain, which can become more severe over time.
Are Cavities Genetic? The Root Cause
Bad Teeth Genes: Can Dental Issues Run In Families?
Are UTIs Genetic?
Have you ever wondered why, despite a perfect bedtime routine, you find yourself waking up precisely at 4 AM? While the reasons behind this early awakening vary widely, they often reflect a complex interplay of hormonal rhythms, lifestyle choices, environmental factors, and genetic makeup. Recent advancements in genetic research show how our DNA can influence sleep patterns and susceptibility to sleep disturbances. In this article, we explore the intersection of nature and nurture and how it can make you wake up at the same time every night.
Did You Know?
Sleep disturbances could strongly affect your well-being.
Diet and lifestyle matter, but it’s essential to understand how genes factor in. Learn more:
Getting a good night’s sleep is relaxing, rejuvenating, and essential for the body.
Everyone needs different amounts of sleep, but most experts agree that seven to eight hours each night is healthy.
Though the amount of sleep one requires varies, adults must get seven to eight hours of it every day.
However, not everyone is lucky enough to get good sleep each night.
Disturbed sleep could be due to:
Sleep is periodic and can be divided into cycles.
In the first cycle, your brain prepares to fall into deeper sleep as you wind down.
Subsequently, your brain’s pineal gland secretes the hormone melatonin.
Melatonin puts you to sleep as your body detoxifies.
As morning approaches, around 4 AM or so, melatonin levels fall.
In response, your brain stimulates the adrenal glands to release cortisol.
Since cortisol is the stress hormone, it tends to “activate” your body.
This response could wake you up at 4 AM every morning.
You could also be waking up in the middle of the night due to:
Most of us wake up at least once every night but usually return to sleep immediately.
It’s a normal part of our natural sleep cycle.
With age, sleep patterns change, and the brain adapts.
Consult a doctor if you wake up several times at night and have sleep issues that regularly impact your day.
Here are a few handy tips for good sleep hygiene:
Waking up at the same time every night or experiencing disturbed sleep can be a byproduct of many sleep aspects, including circadian rhythm and sleep disorders.
No single gene directly determines your likelihood of waking up at 4 AM each night.
Your genetics may still contribute to this issue by influencing several aspects of sleep health.
At 4 AM, melatonin levels drop, and cortisol levels rise.
Since cortisol is the stress hormone, you may feel stressed or anxious at 4 AM.
A warm bedroom environment is usually the culprit.
Sometimes, medications or medical conditions could affect your body’s temperature regulation.
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Though most oral health conditions are preventable, 3.5 billion people worldwide suffer from cavities, gum diseases, and oral cancer. According to the Centre for Disease Control, 90% of adults 20 years and older have had at least one cavity in their permanent teeth during their lifetime. While some people have chronic and frequent dental cavity issues, other people avoid dental visits for years at a stretch! Could this mean dental cavities are genetic?
Dental cavities or regions of tooth decay are permanently damaged areas of tooth structure that result in cavitation(the formation of a hole) in the tooth’s structure.
Dental cavities occur due to:
Dental plaque is a thin, colorless, sticky film that covers the surfaces of teeth.
It harbors bacteria, food particles, and saliva when you eat.
If you don’t brush your teeth properly, plaque builds up and can harden.
Hardened plaque is called tartar; this layer is difficult to remove with simple brushing.
Dental plaque is an essential factor in the initiation of tooth decay.
Tooth cavities occur in five stages:
Bacteria in the plaque begin to produce acids.
These acids start demineralizing (dissolving) the enamel, the outer layer of your tooth.
As enamel begins to lose minerals, it forms a white spot on the teeth.
The white spot darkens to a brownish shade as the enamel breaks down further.
It eventually forms a cavity that a dentist can fill up and prevent from worsening.
You may not have any other signs or symptoms at this stage.
The decay progresses into the middle tooth layer, called the dentine.
Dentine is softer than enamel and tends to decay faster.
The dentine layer houses the tooth nerves.
That’s why your teeth suddenly become sensitive to hot or cold foods or drinks.
The decay reaches the innermost layer of the tooth, called the pulp.
The pulp contains nerves and blood vessels that nourish the tooth.
When tooth decay irritates the pulp, it starts to swell.
The pulp cannot swell freely since the tooth’s structure is firm.
It begins to apply pressure on the nerves and tissues below.
This pressure triggers the pain commonly associated with cavities.
An inflamed pulp causes an abscess (a pocket of pus) to form at the bottom of your tooth.
The infection could spread to nearby tissues if abscesses aren’t immediately addressed and drained.
The treatment for tooth cavities depends upon the stage at which you report to your dentist.
It can range from a simple filling to a tooth removal.
There is ample research to show that cavities are genetic.
Genes influence various factors that could increase your risk for cavities.
Amelogenesis is the process of the formation of the enamel.
This process determines the tooth’s size, shape, color, and likelihood of decay.
Genes could alter the proteins that are a part of this process.
This change, in turn, could affect the likelihood of cavity formation.
Streptococcus mutans is a bacterium present in a healthy oral cavity.
Your immune response influences the growth of this bacteria in the mouth.
Some gene changes result in weaker immune responses, which can lead to irregular growth of S.mutans.
This bacterial growth can increase your risk of cavities.
Some people have a genetic inclination to prefer sweet food more than others.
They seek out higher amounts of sweet foods.
Eating too many sweet foods can increase your risk of tooth cavities.
Saliva flow and consistency play a role in tooth decay and other oral diseases.
When saliva is thin and free-flowing, it can easily wash away bacteria from your teeth.
Thinner saliva reduces your risk of gum disease or other infections.
On the other hand, having less saliva increases the risk of tooth decay.
Studies have shown that women have less saliva than men, putting them at risk for tooth decay.
Saliva comprises various electrolytes, including sodium, potassium, calcium, magnesium, bicarbonate, and phosphates. They help inhibit caries formation and progression.
Specific gene changes result in inadequate electrolytes in saliva, increasing the risk for cavities.
The oral microbiome is the collection of microbes residing in your mouth.
It can lead to the development of numerous oral infectious diseases, including dental caries, periodontitis, and peri-implant disease.
Genetic factors can contribute to the imbalance in the gut microbiome, resulting in an increased risk for all these conditions.
An imbalanced gut microbiome increases your risk for all these conditions.
Besides the causes of tooth cavities mentioned above, other lesser-known factors include:
Tooth cavities are highly preventable, and here are a few practical tips for doing so, regardless of genetics:
Enamel damage can heal over time.
A cavity that has reached the dentine or pulp needs medical attention.
It isn’t always the case.
Certain foods can leave some stains on your teeth, discoloring them.
Mouthwash can significantly reduce the probability of getting a cavity.
However, an existing cavity from tooth decay needs medical attention.
Bad Teeth Genes: Can Dental Issues Run In Families?
Are UTIs Genetic?
How It Works: Are Freckles Genetic?
The curly girl method took the internet by storm and became a much-needed blessing for all those flaunting their gorgeous curls. It has helped enhance the look of the natural curls for many. But curls are more than just a style statement; it’s a genetic code embedded in your DNA. But is curly hair genetic, or does the environment play its tune?
Understanding your hair type helps explain how genetics influence your locks. Hair is commonly categorized using the Andre Walker Hair Typing System, which ranges from Type 1 (straight) to Type 4 (coily). Here’s a simple breakdown:
| Different Types Of Hair Patterns | |
| Type 1: Straight Hair Straight hair is smooth and lacks any natural curl or wave. It’s known for its sleek appearance and ability to reflect light, giving it a shiny look. | |
| 1A | Very straight and fine, with little volume or body |
| 1B | Straight but with more texture and medium thickness |
| 1C | Straight with coarse strands, prone to slight waves and frizz |
| Type 2: Wavy Hair Wavy hair sits between straight and curly hair types. It has an “S” shape and can range from loose, subtle waves to more defined ones. | |
| 2A | Soft, loose waves with a fine texture |
| 2B | Defined “S”-shaped waves, more prone to frizz |
| 2C | Deep waves nearing curls, thick and resilient hair |
| Type 3: Curly Hair Curly hair forms distinct loops and spirals. The curls can vary from loose rings to tight corkscrews. | |
| 3A | Large, loose curls about the size of sidewalk chalk |
| 3B | Bouncy ringlets similar in size to a marker |
| 3C | Tight curls the diameter of a pencil, voluminous and springy |
| Type 4: Coily Hair Coily hair, also known as kinky or afro-textured hair, features tight curls in a zigzag pattern. The strands are densely packed and can shrink significantly when dry due to the tight curl pattern. | |
| 4A | Dense, spring-like coils about the size of a crochet needle |
| 4B | Z-shaped coils with sharp angles and less defined patterns |
| 4C | Tightly coiled with minimal definition, highly prone to shrinkage |
Genetics plays a crucial role in determining various characteristics of your hair. Here are some key aspects influenced by your genetic makeup:
The shape of your hair follicles—determined by genetics—largely dictates whether your hair is straight, wavy, curly, or coily. Round follicles produce straight hair, while oval or twisted follicles result in wavy or curly hair.
Natural hair color depends on the type and amount of melanin pigments. Genes influence whether you have more eumelanin (leading to black or brown hair) or pheomelanin (resulting in red or blonde hair).
Genetic factors determine the thickness of individual hair strands and the overall density of hair follicles on your scalp.
The rate at which your hair grows and its maximum potential length are genetically predetermined. Genes influence the duration of the anagen (growth) phase of the hair cycle, affecting how long your hair can grow.
Conditions like androgenetic alopecia (male or female pattern baldness) are influenced by genetics. Specific genes can make hair follicles more sensitive to hormones like dihydrotestosterone (DHT), leading to gradual hair thinning and loss.
The onset of graying is also genetically controlled. Genes affect the decline in melanin production over time, which causes hair to lose its color and turn gray or white.
Yes, curly hair is genetic – however, there’s no one single gene responsible for it.
The genetics behind hair curliness is complex and multifactorial.
Several genes have been implicated in determining hair texture, but a prominent one that has been studied in relation to hair curliness is the TCHH (trichohyalin) gene.
The protein produced by the TCHH gene plays a role in the development of the hair shaft.
It is localized in the inner root sheath of hair follicles.
Variations or differences in this gene have been associated with the difference in hair curliness across populations.
A 2009 study identified a genetic variant in the TCHH gene that is responsible for 6% of the variance in curly, wavy, and straight hair.
However, it’s essential to understand that the presence or absence of this variant doesn’t guarantee straight or curly hair but rather influences the odds.
Other genes like EDAR and FGFR2 have also been linked to hair texture.
The interplay between multiple genes, each with its variants, determines the final hair phenotype, making the genetics of hair curliness a complex trait.
Curly hair, from a genetic standpoint, tends to be a dominant trait.
Dominant traits are those that overpower recessive ones. Dominant traits need only a single copy from either biological parent to be expressed.
On the other hand, recessive traits need two copies, one from each biological parent, to be expressed.
Straight hair is a recessive trait.
However, like many genetic traits, hair type isn’t a straightforward dominant or recessive game.
If both parents have a combination of genes (one for straight and one for curly hair), their offspring can exhibit a range of hair textures.
Even within families with a strong prevalence of curly hair, hair type could vary significantly, emphasizing the complex interplay of genes.
Did You Know?
Not just hair, but many aspects of your skin, from the risk for premature wrinkles and acne to your ideal skincare routine, are influenced heavily by your genes! Your ancestry test DNA data includes 700,000 markers, which can be used to learn in-depth about your skin aging and skin health. This report will help you understand your skin requirements better and aid in graceful aging. Learn more.
Some reports say that less than 20% of the world’s population have proper curly hair, making it rarer than straight or wavy hair.
The hair spectrum includes rare types like Type 1c (straight and thick) and Type 4c (tight coils with zigs and zags).
The prevalence of these types varies by ethnicity and region.
Genetics lays the foundation, but environment and lifestyle choices build upon it.
Hormonal changes, nutritional choices, stress, and even hair care routines can shift hair texture over time.
For instance, prolonged exposure to humidity or salty water can influence hair’s texture.
Prolonged heat treatments or chemical applications can lead to a permanent change in hair type.
Additionally, hormonal fluctuations, especially during pregnancy or menopause, can lead to hair texture modifications.
While genetics favor curly hair offspring, if one or both parents possess curly hair, it isn’t absolute.
Genes can sometimes skip generations.
So, even if your parents do not have curly hair if someone in the previous generations did, there’s a chance of you having curly hair.
Both parents contribute genes, so neither parent singularly determines curly hair.
It’s the combination of genes from both that paints the final picture.
Absolutely. The mystery of genetics means that if both parents carry the recessive curly hair gene, their child could very well sport a curly mane.
Naturally, curly hair is relatively common but varies by population and ethnicity.
Globally, it’s estimated that about 11% of people have naturally curly hair.
The prevalence can be higher or lower in specific regions due to genetic diversity and ancestral backgrounds.
Curly hair is found across all ethnicities, though its prevalence and type can vary.
It is common among people of African descent, who often have tightly coiled hair.
Wavy and curly hair types are also prevalent in Middle Eastern, European, South Asian, and Latin American populations due to diverse genetic backgrounds.
Our hair’s texture, whether curly or straight, often prompts the question: “Is hair type genetic?” Delving into the science behind our locks reveals that genes, such as TCHH, play a crucial role in shaping our hair’s form, confirming that curly hair is genetic. While genetics typically suggests that curly traits tend to dominate, it’s not the sole influencer. Environment and lifestyle choices weave into the narrative, adding depth to the story of every curl and strand.
https://pubmed.ncbi.nlm.nih.gov/5173315/
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006594
https://medlineplus.gov/genetics/gene/tchh/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775823/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432488/
LifeDNA and 10X Health are two major players in the field of genetic testing. They both offer well-reputed tests to unlock insights into your DNA. Their reports provide valuable recommendations to help improve overall health and wellness. This article compares both companies based on report quality, pricing, user experience, user reviews, and privacy policies. LifeDNA or 10X Health? By the end of this article, you’ll be able to make the right call.
LifeDNA was founded in 2017 by Steve Markowitz.
It is headquartered in Hawaii and specializes in DNA-based health and wellness services.
LifeDNA offers three pricing plans for their genetic tests, ranging from $99 to $249.
10X Health is a company that provides personalized health solutions.
These include genetic tests, blood tests, multivitamin supplements, and more.
10X provides two kinds of genetic tests centered around health and nutrition.
They are priced at $599 and $1,299 respectively.
10X Health’s reports come with a 400-page guidebook that contains detailed information on each trait analyzed.
It also provides recommendations for nearly every facet of health and wellness.
LifeDNA provides shorter reports with clear trait outcomes and recommendations where applicable.
Both reports present their results lucidly.
Between the two companies, 10X Health has the more expensive reports.
They offer a genetic test for $599 and a precision genetic test for $1,299
Their Precision Genetic Test results include a 400-page guide to optimal nutrition and fitness.
The report prescribes personalized supplements to help manage health and weight, but you must purchase them separately.
On the other hand, LifeDNA offers better value for money.
They offer 3 products: a methylation test for $99, a wellness bundle for $199, and a wellness bundle with a DNA kit for $249.
Their plans contain reports on dozens of traits with actionable recommendations.
After receiving your DNA sample, LifeDNA can take up to 2 weeks to deliver their reports.
Since shipping a DNA kit can take time, LifeDNA allows you to upload raw DNA data from a few other genetic testing services.
10X Health takes 6 to 8 weeks to return genetic test results and doesn’t seem to accept DNA from raw data providers.
LifeDNA has a 4.0 score on Trustpilot.
Most users are satisfied with the presentation of their results and prompt customer service.
On the other hand, 10X Health has a score of 1.6.
Users aren’t happy with the generic nature of their reports and prescriptions.
While 10X Health has reached a wider audience, LifeDNA has better word of mouth online.
LifeDNA is transparent about user data security.
Each user’s data is encrypted safely, and the user has full control over it.
LifeDNA does not use or share genetic data for research or commercial purposes without the user’s consent.
Read LifeDNA’s privacy policy here.
10X’s privacy policy mentions 11 kinds of data they collect from their users.
They use this data to create a customer profile, which helps curate your experience on the site and the report’s content.
They may use this data for targeted advertising and commercial purposes.
Read 10X Health’s privacy policy here.
Some users aren’t satisfied with 10X’s methylation report.
10X Health only analyzes 5 genes for methylation.
In contrast, LifeDNA analyzes 12 genes at a fraction of the price.
Their methylation report also accepts raw DNA data from providers like 23andMe, AncestryDNA, MyHeritage, Living DNA, and FTDNA.
Thus, LifeDNA is the better choice for methylation genetic testing.
LifeDNA is a good pick for people who take a casual interest in genetic DNA testing.
Their reports are concise and delivered faster than 10X Health’s reports.
LifeDNA’s recommendations are contained within their reports, so it isn’t the right choice for people looking to overhaul their health and wellness lifestyle.
10X Health is the better option for people who want to make active changes in their lifestyle.
10X prescribes specific supplements to help with nutrition and fitness, which could improve your health in the long run.
Due to its pricing, 10X is not the right choice for people who want to understand their genetic makeup in a casual sense.
| Criterion | LifeDNA | 10X Health |
| Report Quality | Shorter, more concise | Longer, more detailed |
| Pricing | 3 reports: $99, $199, $249 | 2 reports: $599, $1,299 |
| User Experience | Reports delivered faster, better customer support | Reports delivered slower, poorer customer support |
| User Reviews | 4.0 stars on Trustpilot | 1.6 stars on Trustpilot |
| Methylation Genetic Testing | More genes analyzed | Less genes analyzed |
While 10X Health is a decent choice for genetic testing, LifeDNA is the better choice due to:
Understanding your body’s methylation processes with a genetic test is worth it.
It can help you address health risks to improve your overall well-being.
Xcode Life offers a comprehensive suite of reports at an affordable price.
Xcode delivers its reports within 24 hours and offers a free consultation on the results.
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