COMT gene influences the metabolization of dopamine. A variant in the COMT gene results in a lower enzymatic activity, and thereby higher dopamine levels. The A allele carriers are considered to be the "Worrier" (AA) genotype. The G variant results in higher enzymatic activity, and lower dopamine levels. The GG carriers are assigned the "Warrior" genotype. Carriers of the third genotype, AG are intermediate metabolizers of Dopamine. They are assigned a status that is both a warrior or worrier and which one of these traits dominates may depend on some external factors including lifestyle and environment.
