Enter Gene or Traits or Disease
Gene: A1CF
Alternate names for this Gene: ACF|ACF64|ACF65|APOBEC1CF|ASP
Gene Summary: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene is located in Chromosome: 10
Location in Chromosome : 10q11.23
Description of this Gene: APOBEC1 complementation factor
Type of Gene: protein-coding