Gene: ABCF1

Alternate names for this Gene: ABC27|ABC50

Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.33

Description of this Gene: ATP binding cassette subfamily F member 1

Type of Gene: protein-coding

Gene: ABCF1-DT

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

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rs3132613 in ABCF1;ABCF1-DT gene and Graves Disease PMID 21900946 2011 Multivariate stepwise logistic regression analysis selected rs3893464, rs4313034, rs3132613, rs4248154, rs2273017, rs9394159 and rs4713693, as markers for independent risk loci for GD.

rs4148247 in ABCF1;ABCF1-DT gene and Influenza due to Influenza A virus subtype H1N1 PMID 26379185 2015 No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity.