Gene: ABLIM3

Alternate names for this Gene: HMFN1661

Gene Summary: This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of adherens junctions in several cell types. A variant of this gene may be associated with pain sensitivity in male human patients.

Gene is located in Chromosome: 5

Location in Chromosome : 5q32

Description of this Gene: actin binding LIM protein family member 3

Type of Gene: protein-coding

rs1109114 in ABLIM3 gene and Body mass index PMID 25673413 2015 Genetic studies of body mass index yield new insights for obesity biology.

rs3839234 in ABLIM3 gene and Forced expiratory volume function PMID 28166213 2017 Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.

rs11743174 in ABLIM3 gene and Glomerular Filtration Rate PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.

rs4490572 in ABLIM3 gene and Vital capacity PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs6884531 in ABLIM3 gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.