Gene: ABT1

Alternate names for this Gene: Esf2|hABT1

Gene Summary: Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.2

Description of this Gene: activator of basal transcription 1

Type of Gene: protein-coding

rs45527431 in ABT1 gene and Major Depressive Disorder PMID 29662059 2018 Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.