Gene: ACBD4
Alternate names for this Gene: HMFT0700
Gene Summary: This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 17
Location in Chromosome : 17q21.31
Description of this Gene: acyl-CoA binding domain containing 4
Type of Gene: protein-coding
Gene: PLCD3
Alternate names for this Gene: PLC-delta-3
Gene Summary: This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
Gene is located in Chromosome: 17
Location in Chromosome : 17q21.31
Description of this Gene: phospholipase C delta 3
Type of Gene: protein-coding