Gene: ACTR3B

Alternate names for this Gene: ARP11|ARP3BETA

Gene Summary: This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.

Gene is located in Chromosome: 7

Location in Chromosome : 7q36.1-q36.2

Description of this Gene: actin related protein 3B

Type of Gene: protein-coding

rs4725479 in ACTR3B gene and Ulcerative Colitis PMID 25082827 2014 A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.