Gene: ADAMTS10
Alternate names for this Gene: ADAM-TS10|ADAMTS-10|WMS|WMS1
Gene Summary: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome.
Gene is located in Chromosome: 19
Location in Chromosome : 19p13.2
Description of this Gene: ADAM metallopeptidase with thrombospondin type 1 motif 10
Type of Gene: protein-coding