Gene: ADAMTS7

Alternate names for this Gene: ADAM-TS 7|ADAM-TS7|ADAMTS-7

Gene Summary: The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease.

Gene is located in Chromosome: 15

Location in Chromosome : 15q25.1

Description of this Gene: ADAM metallopeptidase with thrombospondin type 1 motif 7

Type of Gene: protein-coding

Gene: MORF4L1

Alternate names for this Gene: Eaf3|FWP006|HsT17725|MEAF3|MORFRG15|MRG15|S863-6

Gene Summary:

Gene is located in Chromosome: 15

Location in Chromosome : 15q25.1

Description of this Gene: mortality factor 4 like 1

Type of Gene: protein-coding

rs11634042 in ADAMTS7;MORF4L1 gene and Smoking Behaviors PMID 20418889 2010 Meta-analysis and imputation refines the association of 15q25 with smoking quantity.

PMID 20418888 2010 Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.