Gene: ADAMTSL3
Alternate names for this Gene: ADAMTSL-3
Gene Summary:
Gene is located in Chromosome: 15
Location in Chromosome : 15q25.2
Description of this Gene: ADAMTS like 3
Type of Gene: protein-coding
rs7175718 in
ADAMTSL3 gene and
Adolescent idiopathic scoliosis
PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
rs11856122 in
ADAMTSL3 gene and
Body Fat Distribution
PMID 30664634 2019 Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.
rs10906982 in
ADAMTSL3 gene and
Body Height
PMID 20397748 2010 Genome-wide association study of height and body mass index in Australian twin families.
PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.
PMID 18391952 2008 Genome-wide association analysis identifies 20 loci that influence adult height.
PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.
PMID 23563607 2013 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
PMID 20881960 2010 Hundreds of variants clustered in genomic loci and biological pathways affect human height.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 21998595 2011 Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.
PMID 25429064 2015 Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
PMID 28552196 2017 Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.
PMID 19343178 2009 Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.
PMID 20189936 2010 A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
PMID 25282103 2014 Defining the role of common variation in the genomic and biological architecture of adult human height.
rs10152300 in
ADAMTSL3 gene and
Chronic Obstructive Airway Disease
PMID 30804561 2019 Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
rs10906982 in
ADAMTSL3 gene and
Height
PMID 18391952 2008 Genome-wide association analysis identifies 20 loci that influence adult height.
PMID 20397748 2010 Genome-wide association study of height and body mass index in Australian twin families.
PMID 23563607 2013 Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
PMID 20881960 2010 Hundreds of variants clustered in genomic loci and biological pathways affect human height.
PMID 21998595 2011 Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.
PMID 20189936 2010 A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.
PMID 19343178 2009 Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.
rs7183263 in
ADAMTSL3 gene and
Hip circumference
PMID 25673412 2015 New genetic loci link adipose and insulin biology to body fat distribution.
rs4842924 in
ADAMTSL3 gene and
Lean body mass
PMID 28724990 2017 Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
rs7175718 in
ADAMTSL3 gene and
Narcolepsy
PMID 19629137 2009 Genome-wide association database developed in the Japanese Integrated Database Project.
rs2030839 in
ADAMTSL3 gene and
Physical Activity Measurement
PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
rs7170165 in
ADAMTSL3 gene and
Respiratory Tract Diseases
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs7175718 in
ADAMTSL3 gene and
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
rs2135551 in
ADAMTSL3 gene and
Schizophrenia
PMID 19197363 2009 A genome-wide investigation of SNPs and CNVs in schizophrenia.
PMID 25056061 2014 Biological insights from 108 schizophrenia-associated genetic loci.
PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.
PMID 30285260 2019 Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
PMID 28991256 2017 Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
rs7162542 in
ADAMTSL3 gene and
Smoking
PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
rs7162542 in
ADAMTSL3 gene and
Smoking Behaviors
PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
rs906427 in
ADAMTSL3 gene and
Vital capacity
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs8030379 in
ADAMTSL3 gene and
Waist Circumference
PMID 26785701 2016 Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference.
rs8031704 in
ADAMTSL3 gene and
body fat percentage (physical finding)
PMID 30593698 2019 Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.