Gene: ADD1

Alternate names for this Gene: ADDA

Gene Summary: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.3

Description of this Gene: adducin 1

Type of Gene: protein-coding

rs762847 in ADD1 gene and Huntington Disease PMID 22387017 2012 Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region.