Gene: ADGRA1

Alternate names for this Gene: GPR123

Gene Summary: This gene encodes a protein that belongs to the adhesion family of G-protein-coupled receptors. Members of this family function in several sensory systems and regulate blood pressure, immune responses, food intake and development. A similar protein in rodents is thought to play a role in in the regulation of neuronal signaling pathways. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene is located in Chromosome: 10

Location in Chromosome : 10q26.3

Description of this Gene: adhesion G protein-coupled receptor A1

Type of Gene: protein-coding

rs73399159 in ADGRA1 gene and Thyroglobulin antibody measurement PMID 29678681 2019 Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians.

rs190671939 in ADGRA1 gene and response to bronchodilator PMID 26634245 2015 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.