Gene: AFDN

Alternate names for this Gene: AF6|MLL-AF6|MLLT4|l-afadin

Gene Summary: This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.

Gene is located in Chromosome: 6

Location in Chromosome : 6q27

Description of this Gene: afadin, adherens junction formation factor

Type of Gene: protein-coding

Gene: LOC107986673

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

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Description of this Gene:

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rs2340910 in AFDN;LOC107986673 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.