Gene: AFF3

Alternate names for this Gene: LAF4|MLLT2-like

Gene Summary: This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene is located in Chromosome: 2

Location in Chromosome : 2q11.2

Description of this Gene: AF4/FMR2 family member 3

Type of Gene: protein-coding

Gene: LOC105373504

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