Gene: AFF4

Alternate names for this Gene: AF5Q31|CHOPS|MCEF

Gene Summary: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23).

Gene is located in Chromosome: 5

Location in Chromosome : 5q31.1

Description of this Gene: AF4/FMR2 family member 4

Type of Gene: protein-coding

Gene: ATP6V0E1P1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

rs17691584 in AFF4;ATP6V0E1P1 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.