Gene: AFM

Alternate names for this Gene: ALB2|ALBA|ALF

Gene Summary: This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.

Gene is located in Chromosome: 4

Location in Chromosome : 4q13.3

Description of this Gene: afamin

Type of Gene: protein-coding

rs12510870 in AFM gene and Eye Color PMID 29109912 2017 Genome-wide association study of pigmentary traits (skin and iris color) in individuals of East Asian ancestry.

rs1894292 in AFM gene and Malignant neoplasm of prostate PMID 23535732 2013 Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

rs1894292 in AFM gene and Prostate carcinoma PMID 29892016 2018 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

PMID 23535732 2013 Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.