Gene: AGAP3

Alternate names for this Gene: AGAP-3|CENTG3|CRAG|MRIP-1|cnt-g3

Gene Summary: This gene encodes an essential component of the N-methyl-D-aspartate (NMDA) receptor signaling complex which mediates long-term potentiation in synapses by linking activation of NMDA receptor to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking. The encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains.

Gene is located in Chromosome: 7

Location in Chromosome : 7q36.1

Description of this Gene: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

Type of Gene: protein-coding

rs749319 in AGAP3 gene and Body mass index PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs10952302 in AGAP3 gene and Vital capacity PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.