Gene: AGO3

Alternate names for this Gene: EIF2C3

Gene Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1p34.3

Description of this Gene: argonaute RISC catalytic component 3

Type of Gene: protein-coding

rs491603 in AGO3 gene and Barrett Esophagus PMID 29551738 2018 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.

rs491603 in AGO3 gene and Body mass index PMID 29551738 2018 Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett's Esophagus.