Gene: AIFM2

Alternate names for this Gene: AMID|FSP1|PRG3

Gene Summary: This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells.

Gene is located in Chromosome: 10

Location in Chromosome : 10q22.1

Description of this Gene: apoptosis inducing factor mitochondria associated 2

Type of Gene: protein-coding

rs10999147 in AIFM2 gene and Rheumatoid Arthritis PMID 30891314 2019 Studying the effects of haplotype partitioning methods on the RA-associated genomic results from the North American Rheumatoid Arthritis Consortium (NARAC) dataset.

rs41277978 in AIFM2 gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs139479025 in AIFM2 gene and response to bronchodilator PMID 26634245 2015 A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.