Gene: AIM2

Alternate names for this Gene: PYHIN4

Gene Summary: AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.1-q23.2

Description of this Gene: absent in melanoma 2

Type of Gene: protein-coding

rs11265142 in AIM2 gene and C-reactive protein measurement PMID 22291609 2012 A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation.

rs2276405 in AIM2 gene and Psoriasis PMID 25854761 2015 Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis.

rs1103577 in AIM2 gene and White Blood Cell Count procedure PMID 21738479 2011 Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).

PMID 25096241 2014 Trans-ethnic meta-analysis of white blood cell phenotypes.

PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.