Gene: AKAP8

Alternate names for this Gene: AKAP 95|AKAP-8|AKAP-95|AKAP95

Gene Summary: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.12

Description of this Gene: A-kinase anchoring protein 8

Type of Gene: protein-coding

rs143155169 in AKAP8 gene and Red Blood Cell Count measurement PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.