Gene: AKR1B1

Alternate names for this Gene: ADR|ALDR1|ALR2|AR

Gene Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Gene is located in Chromosome: 7

Location in Chromosome : 7q33

Description of this Gene: aldo-keto reductase family 1 member B

Type of Gene: protein-coding