Gene: AKR7A2

Alternate names for this Gene: AFAR|AFAR1|AFB1-AR1|AKR7

Gene Summary: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.13

Description of this Gene: aldo-keto reductase family 7 member A2

Type of Gene: protein-coding

Gene: SLC66A1

Alternate names for this Gene: LAAT-1|LAAT1|PQLC2

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1p36.13

Description of this Gene: solute carrier family 66 member 1

Type of Gene: protein-coding