Gene: ANKRD26

Alternate names for this Gene: THC2|bA145E8.1

Gene Summary: This gene encodes a protein containing N-terminal ankyrin repeats which function in protein-protein interactions. Mutations in this gene are associated with autosomal dominant thrombocytopenia-2. Pseudogenes of this gene are found on chromosome 7, 10, 13 and 16. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 10

Location in Chromosome : 10p12.1

Description of this Gene: ankyrin repeat domain 26

Type of Gene: protein-coding

rs7081476 in ANKRD26 gene and Atrial Fibrillation PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.

rs112505971 in ANKRD26 gene and Blood basophil count (lab test) PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs10829163 in ANKRD26 gene and Body mass index PMID 29273807 2018 Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

rs7081476 in ANKRD26 gene and Cerebrovascular accident PMID 27790247 2016 Specifically, from Group 2, we find rs7632505 on 3q21.1 in <i>SEMA5B</i>, rs460976 on 21q22.3 (1 kb from <i>TMPRSS2</i>) and rs12420422 on 11q24.1 predominantly associated with a variety of CVDs, rs4905014 in <i>ITPK1</i> associated with stroke and heart failure, rs7081476 on 10p12.1 in <i>ANKRD26</i> associated with multiple diseases including DM, CVDs, and NDs.

rs7081476 in ANKRD26 gene and Coronary heart disease PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.

rs112505971 in ANKRD26 gene and Corpuscular Hemoglobin Concentration Mean PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs7081476 in ANKRD26 gene and Diabetes PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.

rs7081476 in ANKRD26 gene and Diabetes Mellitus PMID 27790247 2016 Specifically, from Group 2, we find rs7632505 on 3q21.1 in <i>SEMA5B</i>, rs460976 on 21q22.3 (1 kb from <i>TMPRSS2</i>) and rs12420422 on 11q24.1 predominantly associated with a variety of CVDs, rs4905014 in <i>ITPK1</i> associated with stroke and heart failure, rs7081476 on 10p12.1 in <i>ANKRD26</i> associated with multiple diseases including DM, CVDs, and NDs.

rs112505971 in ANKRD26 gene and Eosinophil count procedure PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs7081476 in ANKRD26 gene and Heart failure PMID 27790247 2016 Specifically, from Group 2, we find rs7632505 on 3q21.1 in <i>SEMA5B</i>, rs460976 on 21q22.3 (1 kb from <i>TMPRSS2</i>) and rs12420422 on 11q24.1 predominantly associated with a variety of CVDs, rs4905014 in <i>ITPK1</i> associated with stroke and heart failure, rs7081476 on 10p12.1 in <i>ANKRD26</i> associated with multiple diseases including DM, CVDs, and NDs.

rs7081476 in ANKRD26 gene and Malignant Neoplasms PMID 27790247 2016 Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.

rs112505971 in ANKRD26 gene and Mean Corpuscular Volume (result) PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs112505971 in ANKRD26 gene and Monocyte count procedure PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs112505971 in ANKRD26 gene and Monocyte count result PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs112505971 in ANKRD26 gene and Neutrophil count (procedure) PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs112505971 in ANKRD26 gene and Platelet Count measurement PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs112505971 in ANKRD26 gene and Platelet mean volume determination (procedure) PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs112505971 in ANKRD26 gene and RDW - Red blood cell distribution width result PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs10764671 in ANKRD26 gene and Red Blood Cell Count measurement PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs112505971 in ANKRD26 gene and Red cell distribution width determination PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.

rs863223318 in ANKRD26 gene and Thrombocytopenia PMID 31064749 2019 Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders.

rs112505971 in ANKRD26 gene and White Blood Cell Count procedure PMID 31080455 2019 Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits.