Gene: ANLN

Alternate names for this Gene: FSGS8|Scraps|scra

Gene Summary: This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene is located in Chromosome: 7

Location in Chromosome : 7p14.2

Description of this Gene: anillin actin binding protein

Type of Gene: protein-coding

rs587777741 in ANLN gene and FOCAL SEGMENTAL GLOMERULOSCLEROSIS 8 PMID 24676636 2014 Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS.

rs55891665 in ANLN gene and Finding of Mean Corpuscular Hemoglobin PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs10224902 in ANLN gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs10224902 in ANLN gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs3735398 in ANLN gene and Systolic Pressure PMID 26969751 2016 International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents.