Gene: ANXA3

Alternate names for this Gene: ANX3

Gene Summary: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Gene is located in Chromosome: 4

Location in Chromosome : 4q21.21

Description of this Gene: annexin A3

Type of Gene: protein-coding

rs2867461 in ANXA3 gene and Rheumatoid Arthritis PMID 22446963 2012 Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.