Gene: APLP1
Alternate names for this Gene: APLP
Gene Summary: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene is located in Chromosome: 19
Location in Chromosome : 19q13.12
Description of this Gene: amyloid beta precursor like protein 1
Type of Gene: protein-coding
Gene: LOC107985317
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