Gene: ARFRP1

Alternate names for this Gene: ARL18|ARP|Arp1

Gene Summary: The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.33

Description of this Gene: ADP ribosylation factor related protein 1

Type of Gene: protein-coding

rs1758206 in ARFRP1 gene and Glomerular Filtration Rate PMID 31015462 2019 Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.

PMID 30604766 2019 Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.