Gene: ARHGAP11A-SCG5

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: SCG5

Alternate names for this Gene: 7B2|P7B2|SGNE1|SgV

Gene Summary: This gene encodes a secreted chaperone protein that prevents the aggregation of other secreted proteins, including proteins that are associated with neurodegenerative and metabolic disease. The encoded protein may be best known for its role in the trafficking and activation of prohormone convertase PC2 (encoded by Gene ID: 5126). Phosphorylation of the encoded protein has been shown to have an inhibitory effect on its chaperone function. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein.

Gene is located in Chromosome: 15

Location in Chromosome : 15q13.3

Description of this Gene: secretogranin V

Type of Gene: protein-coding

Gene: ARHGAP11A

Alternate names for this Gene: GAP (1-12)

Gene Summary: This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein.

Gene is located in Chromosome: 15

Location in Chromosome : 15q13.3

Description of this Gene: Rho GTPase activating protein 11A

Type of Gene: protein-coding