Gene: ARHGAP25

Alternate names for this Gene: HEL-S-308|KAIA0053

Gene Summary: ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 2

Location in Chromosome : 2p13.3

Description of this Gene: Rho GTPase activating protein 25

Type of Gene: protein-coding

rs10048745 in ARHGAP25 gene and Bone Density PMID 29304378 2018 Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

rs10048745 in ARHGAP25 gene and Platelet Count measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs2311412 in ARHGAP25 gene and Systolic Pressure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.