Gene: ARHGAP5

Alternate names for this Gene: GFI2|RhoGAP5|p190-B|p190BRhoGAP

Gene Summary: Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 14

Location in Chromosome : 14q12

Description of this Gene: Rho GTPase activating protein 5

Type of Gene: protein-coding

rs140783387 in ARHGAP5 gene and Breast Carcinoma PMID 29059683 2017 Association analysis identifies 65 new breast cancer risk loci.

rs7140954 in ARHGAP5 gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.