Gene: ARHGEF10
Alternate names for this Gene: GEF10|SNCV
Gene Summary: This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.
Gene is located in Chromosome: 8
Location in Chromosome : 8p23.3
Description of this Gene: Rho guanine nucleotide exchange factor 10
Type of Gene: protein-coding