Gene: ARHGEF7

Alternate names for this Gene: BETA-PIX|COOL-1|COOL1|Nbla10314|P50|P50BP|P85|P85COOL1|P85SPR|PAK3|PIXB

Gene Summary: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Gene is located in Chromosome: 13

Location in Chromosome : 13q34

Description of this Gene: Rho guanine nucleotide exchange factor 7

Type of Gene: protein-coding