Gene: ARID3A

Alternate names for this Gene: BRIGHT|DRIL1|DRIL3|E2FBP1

Gene Summary: This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.3

Description of this Gene: AT-rich interaction domain 3A

Type of Gene: protein-coding

rs349306 in ARID3A gene and Age at menopause PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 26414677 2015 Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

rs10415976 in ARID3A gene and Primary biliary cirrhosis PMID 28425483 2017 A genome-wide association study identifies six novel risk loci for primary biliary cholangitis.

rs62132342 in ARID3A gene and Reticulocyte count (procedure) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.