Gene: ARMC2

Alternate names for this Gene: SPGF38|bA787I22.1

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: armadillo repeat containing 2

Type of Gene: protein-coding

Gene: SESN1

Alternate names for this Gene: PA26|SEST1

Gene Summary: This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6q21

Description of this Gene: sestrin 1

Type of Gene: protein-coding