Gene: ASF1B

Alternate names for this Gene: CIA-II

Gene Summary: This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.

Gene is located in Chromosome: 19

Location in Chromosome : 19p13.12

Description of this Gene: anti-silencing function 1B histone chaperone

Type of Gene: protein-coding

rs7249561 in ASF1B gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.