Gene: ASH2L

Alternate names for this Gene: ASH2|ASH2L1|ASH2L2|Bre2

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8p11.23

Description of this Gene: ASH2 like, histone lysine methyltransferase complex subunit

Type of Gene: protein-coding

rs2517388 in ASH2L gene and Age at menopause PMID 22267201 2012 Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

PMID 23307926 2013 A genome-wide association study of early menopause and the combined impact of identified variants.

PMID 26414677 2015 Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.