Gene: ATF4

Alternate names for this Gene: CREB-2|CREB2|TAXREB67|TXREB

Gene Summary: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.1

Description of this Gene: activating transcription factor 4

Type of Gene: protein-coding

Gene: MIEF1

Alternate names for this Gene: AltMIEF1|HSU79252|MID51|MIEF1-MP|SMCR7L|dJ1104E15.3

Gene Summary:

Gene is located in Chromosome: 22

Location in Chromosome : 22q13.1

Description of this Gene: mitochondrial elongation factor 1

Type of Gene: protein-coding