Gene: ATG5
Alternate names for this Gene: APG5|APG5-LIKE|APG5L|ASP|SCAR25|hAPG5
Gene Summary: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Gene is located in Chromosome: 6
Location in Chromosome : 6q21
Description of this Gene: autophagy related 5
Type of Gene: protein-coding
Gene: PRDM1
Alternate names for this Gene: BLIMP1|PRDI-BF1
Gene Summary: This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
Gene is located in Chromosome: 6
Location in Chromosome : 6q21
Description of this Gene: PR/SET domain 1
Type of Gene: protein-coding