Gene: ATP23

Alternate names for this Gene: KUB3|XRCC6BP1

Gene Summary: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 12

Location in Chromosome : 12q14.1

Description of this Gene: ATP23 metallopeptidase and ATP synthase assembly factor homolog

Type of Gene: protein-coding