Gene: AURKA

Alternate names for this Gene: AIK|ARK1|AURA|BTAK|PPP1R47|STK15|STK6|STK7

Gene Summary: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Gene is located in Chromosome: 20

Location in Chromosome : 20q13.2

Description of this Gene: aurora kinase A

Type of Gene: protein-coding

rs2180691 in AURKA gene and Finding of Mean Corpuscular Hemoglobin PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.