Gene: AVEN

Alternate names for this Gene: PDCD12

Gene Summary:

Gene is located in Chromosome: 15

Location in Chromosome : 15q14

Description of this Gene: apoptosis and caspase activation inhibitor

Type of Gene: protein-coding

Gene: CHRM5

Alternate names for this Gene: HM5

Gene Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.

Gene is located in Chromosome: 15

Location in Chromosome : 15q14

Description of this Gene: cholinergic receptor muscarinic 5

Type of Gene: protein-coding

rs661968 in AVEN;CHRM5 gene and Systemic Scleroderma PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.