Gene: BAG1

Alternate names for this Gene: BAG-1|HAP|RAP46

Gene Summary: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Gene is located in Chromosome: 9

Location in Chromosome : 9p13.3

Description of this Gene: BAG cochaperone 1

Type of Gene: protein-coding

Gene: CHMP5

Alternate names for this Gene: C9orf83|CGI-34|HSPC177|PNAS-2|SNF7DC2|Vps60

Gene Summary: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008].

Gene is located in Chromosome: 9

Location in Chromosome : 9p13.3

Description of this Gene: charged multivesicular body protein 5

Type of Gene: protein-coding