Gene: BAK1

Alternate names for this Gene: BAK|BAK-LIKE|BCL2L7|CDN1

Gene Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.31

Description of this Gene: BCL2 antagonist/killer 1

Type of Gene: protein-coding

Gene: GGNBP1

Alternate names for this Gene: -

Gene Summary: This gene is the ortholog of the mouse gametogenetin-binding protein 1 gene. In human, the open reading frame is disrupted by a nonsense mutation after 8-aa; consequently, this gene is currently considered to be a unitary pseudogene in human even though it is functional in other mammals.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.31

Description of this Gene: gametogenetin binding protein 1 (pseudogene)

Type of Gene: pseudo