Gene: BAZ2B

Alternate names for this Gene: WALp4

Gene Summary: This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD).

Gene is located in Chromosome: 2

Location in Chromosome : 2q24.2

Description of this Gene: bromodomain adjacent to zinc finger domain 2B

Type of Gene: protein-coding

rs1011770 in BAZ2B gene and Cholecystolithiasis PMID 17632509 2007 A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.

rs1011770 in BAZ2B gene and Cholelithiasis PMID 17632509 2007 A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.

rs11898293 in BAZ2B gene and Hypothyroidism PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs174230 in BAZ2B gene and Sudden Cardiac Arrest PMID 21738491 2011 Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.

rs4665058 in BAZ2B gene and Sudden Cardiac Death PMID 21738491 2011 Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.

rs62173239 in BAZ2B gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.