Gene: BCO1

Alternate names for this Gene: BCDO|BCDO1|BCMO|BCMO1|BCO

Gene Summary: Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.

Gene is located in Chromosome: 16

Location in Chromosome : 16q23.2

Description of this Gene: beta-carotene oxygenase 1

Type of Gene: protein-coding

rs4889294 in BCO1 gene and Interleukin 1 Beta Measurement PMID 18464913 2008 A genome-wide association study identifies protein quantitative trait loci (pQTLs).

rs4889293 in BCO1 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.