Gene: BDNF-AS

Alternate names for this Gene: ANTI-BDNF|BDNF|BDNF-AS1|BDNFAS|BDNFOS|NCRNA00049

Gene Summary:

Gene is located in Chromosome: 11

Location in Chromosome : 11p14.1

Description of this Gene: BDNF antisense RNA

Type of Gene: ncRNA

Gene: BDNF

Alternate names for this Gene: ANON2|BULN2

Gene Summary: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

Gene is located in Chromosome: 11

Location in Chromosome : 11p14.1

Description of this Gene: brain derived neurotrophic factor

Type of Gene: protein-coding

rs2049045 in BDNF-AS;BDNF gene and Body mass index PMID 31453325 2019 Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank.

PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

rs8192466 in BDNF-AS;BDNF gene and Congenital central hypoventilation PMID 20208042 2010 An official ATS clinical policy statement: Congenital central hypoventilation syndrome: genetic basis, diagnosis, and management.

PMID 11840487 2002 Idiopathic congenital central hypoventilation syndrome: evaluation of brain-derived neurotrophic factor genomic DNA sequence variation.

rs2049045 in BDNF-AS;BDNF gene and Physical Activity Measurement PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

rs6484320 in BDNF-AS;BDNF gene and Smoking Behaviors PMID 22832964 2012 Genome-wide meta-analyses of smoking behaviors in African Americans.