Gene: BICD1

Alternate names for this Gene: BICD|bic-D 1

Gene Summary: This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema.

Gene is located in Chromosome: 12

Location in Chromosome : 12p11.21

Description of this Gene: BICD cargo adaptor 1

Type of Gene: protein-coding

rs708224 in BICD1 gene and Malignant neoplasm of pancreas PMID 20686608 2010 Genome-wide association study of pancreatic cancer in Japanese population.

rs708224 in BICD1 gene and Pancreatic carcinoma PMID 20686608 2010 Genome-wide association study of pancreatic cancer in Japanese population.

rs10844154 in BICD1 gene and Pathological accumulation of air in tissues PMID 20709820 2011 Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.

rs10844154 in BICD1 gene and Pulmonary Emphysema PMID 20709820 2011 Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.

rs11051873 in BICD1 gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.