Gene: BTG4
Alternate names for this Gene: APRO3|OOMD8|PC3B
Gene Summary: The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle.
Gene is located in Chromosome: 11
Location in Chromosome : 11q23.1
Description of this Gene: BTG anti-proliferation factor 4
Type of Gene: protein-coding
Gene: POU2AF1
Alternate names for this Gene: BOB1|OBF-1|OBF1|OCAB
Gene Summary:
Gene is located in Chromosome: 11
Location in Chromosome : 11q23.1
Description of this Gene: POU class 2 homeobox associating factor 1
Type of Gene: protein-coding
rs4938534 in
BTG4;POU2AF1 gene and
Biliary cirrhosis
PMID 23000144 2012 Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.
rs4938534 in
BTG4;POU2AF1 gene and
Primary biliary cirrhosis
PMID 28062665 2017 A previous genome-wide association study (GWAS) performed in 963 Japanese individuals (487 primary biliary cholangitis [PBC] cases and 476 healthy controls) identified TNFSF15 (rs4979462) and POU2AF1 (rs4938534) as strong susceptibility loci for PBC.
PMID 23000144 2012 Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.